GTX23372
MRP2 antibody [M2I-4]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX23372
- Zusätzliche Namen:
- ATP binding cassette subfamily C member 2 , ABC30 , CMOAT , DJS , MRP2 , cMRP
- Anwendung:
- Flow Cytometry, WB, IHC-Fr, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 0.1% Sodium azide.
- Immunogen:
- Bacterial fusion protein of human MRP 2 containing amino acids of 215-310.
- Klon:
- M2I-4
- Uniprot:
- Q92887
- Synonyme:
- ABC30;ATP-binding cassette sub-family C member 2;ATP-binding cassette, sub-family C (CFTR/MRP), member 2;canalicular multidrug resistance protein;canalicular multispecific organic anion transporter 1;CMOAT;cMRP;DJS;MRP2;multidrug resistance-associated protein 2
- Weitere Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice