GTX23370
MRP1 antibody [QCRL3]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX23370
- Zusätzliche Namen:
- ATP binding cassette subfamily C member 1 , ABC29 , ABCC , GS-X , MRP , MRP1
- Anwendung:
- IHC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Lagerbedingungen:
- 2-8[o]C
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 0.1% Sodium azide.
- Immunogen:
- Membranes prepared from the human small cell lung cancer cell line H69AR which highly overexpresses MRP
- Klon:
- QCRL3
- Uniprot:
- P33527
- Synonyme:
- ABC29;ABCC;ATP-binding cassette sub-family C member 1;ATP-binding cassette transporter variant ABCC1delta-ex13;ATP-binding cassette transporter variant ABCC1delta-ex13&14;ATP-binding cassette transporter variant ABCC1delta-ex25;ATP-binding cassette transporter variant ABCC1delta-ex25&26;ATP-binding cassette, sub-family C (CFTR/MRP), member 1;DFNA77;glutathione S-conjugate export pump;glutathione-S-conjugate-translocating ATPase ABCC1;GS-X;leukotriene C(4) transporter;LTC4 transporter;MRP;MRP1;multidrug resistance-associated protein 1
- Weitere Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
- Versandbedingungen:
- Blue Ice