GTX22902
Grp78 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX22902
- Zusätzliche Namen:
- heat shock protein 5 , AL022860 , AU019543 , Bip , D2Wsu141e , D2Wsu17e , Grp78 , Hsce70 , SEZ-7 , Sez7 , baffled , mBiP
- Anwendung:
- WB, IF, ICC, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Rat
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Canine, Hamster, Human, Mouse, Rat, Insect/Arthropod
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to residues C T(643) G E E D T S E K D E L(654) of rat GRP78.
- Uniprot:
- P20029
- Synonyme:
- 78 kDa glucose-regulated protein;78kD;AL022860;AU019543;B;baffl;baffled;binding-immunoglobulin protein;Bip;D2Wsu141;D2Wsu141e;D2Wsu17;D2Wsu17e;endoplasmic reticulum chaperone BiP;glucose regulated protein, 78 kDa;Grp;GRP-78;Grp78;heat shock 70 kDa protein 5;heat shock 70kD protein 5 (glucose-regulated protein, 78kD);heat shock protein 70 family protein 5;heat shock protein family A member 5;Hsce7;Hsce70;HSP70 family protein 5;immunoglobulin heavy chain-binding protein;mB;mBiP;Sez;SEZ-7;Sez7;XAP-1 antigen
- Weitere Details:
- The 78 kDa glucose regulated protein/BiP (GRP78) belongs to the family of ~70 kDa heat shock proteins (HSP70). GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins. GRP78 may also interact with mutant and misfolded proteins, marking them for degredation. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI). The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER.
- Versandbedingungen:
- Blue Ice