Sodium/Potassium ATPase alpha 1 antibody [M7-PB-E9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX22871
Zusätzliche Namen:: ATPase Na+/K+ transporting subunit alpha 1
Anwendung:: ELISA, Flow Cytometry, IHC, WB, IHC-P, IF, ICC, IP
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Sheep
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Bovine, Canine, Human, Mouse, Porcine, Rat, Ovine
Buffer:: Buffer, 0.1% BSA, 0.05% Sodium azide.
Immunogen:: Purified alpha sodium/potassium ATPase from sheep kidney.
Klon:: M7-PB-E9
Uniprot:: P04074
Synonyme:: Na(+)/K(+) ATPase alpha-1 subunit;sodium pump 1;sodium pump subunit alpha-1;sodium/potassium-transporting ATPase alpha-1 chain;sodium/potassium-transporting ATPase subunit alpha-1
Weitere Details:: The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium/potassium ATPase exhibit tissue-specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression. The alpha subunit has been found in kidney, brain, heart, and to a lesser extent liver, skeletal and smooth muscle.

Versandbedingungen:: Blue Ice