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GTX22852

LAT antibody [LAT-01]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX22852
Zusätzliche Namen:
LAT , LAT1 , linker for activation of Tcells , pp36 , linker for activation of T cells
Anwendung:
Flow Cytometry, WB, IP
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
2-8[o]C Do not freeze.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
Bacterially produced recombinant polypeptide corresponding to the entire cytoplasmic domain of human LAT.
Klon:
LAT-01
Uniprot:
O43561
Synonyme:
36 kDa phospho-tyrosine adapter protein;36 kDa phospho-tyrosine adaptor protein;IMD52;LAT1;linker for activation of T cells, transmembrane adaptor;linker for activation of T-cells family member 1;p36-38;pp36
Weitere Details:
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice