GTX22851
DNMT3B antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX22851
- Zusätzliche Namen:
- DNA methyltransferase 3B , MmuIIIB
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 0.1% BSA, 0.05% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to the residues M(1) K G D S R H L N E E E G A(14) C of mouse DNMT3b
- Uniprot:
- O88509
- Synonyme:
- DNA (cytosine-5)-methyltransferase 3B;DNA methyltransferase MmuIIIB;DNA MTase MmuIIIB;MmuIIIB
- Weitere Details:
- This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Nov 2012]
- Versandbedingungen:
- Blue Ice