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GTX22783

PMCA4 ATPase antibody [JA9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX22783
Zusätzliche Namen:
ATPase plasma membrane Ca2+ transporting 4 , ATP2B2 , MXRA1 , PMCA4 , PMCA4b , PMCA4x
Anwendung:
ELISA, Flow Cytometry, WB, IHC-P, IHC-Fr, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Bovine, Human, Porcine, Rat
Buffer:
PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:
Purified human erythrocyte PMCA.
Klon:
JA9
Uniprot:
P23634
Synonyme:
ATP2B2;ATPase, Ca++ transporting, plasma membrane 4;matrix-remodeling-associated protein 1;MXRA1;Plasma membrane calcium ATPase isoform 4;Plasma membrane calcium pump isoform 4;plasma membrane calcium-transporting ATPase 4;PMCA4;PMCA4b;PMCA4x;sarcolemmal calcium pump
Weitere Details:
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice