GTX22507
LAT antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX22507
- Zusätzliche Namen:
- LAT,LAT1,linker for activation of Tcells,pp36,linker for activation of T cells
- Anwendung:
- ELISA, IHC, WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- 10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
- Immunogen:
- Synthetic peptide CHRLPGSYDSTSSDSLYPRGI corresponding to amino acids 29-49 at N-terminus of human pp36, a tyrosine-phosporylated adaptor protein.
- Uniprot:
- O43561
- Synonyme:
- 36 kDa phospho-tyrosine adapter protein;36 kDa phospho-tyrosine adaptor protein;IMD52;LAT1;linker for activation of T cells, transmembrane adaptor;linker for activation of T-cells family member 1;p36-38;pp36
- Weitere Details:
- The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice