GTX22424
STAT6 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX22424
- Zusätzliche Namen:
- signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.2% Gelatin, 0.1% Sodium azide.
- Immunogen:
- Peptide mapping to the carboxy terminus of human Stat6.
- Uniprot:
- P42226
- Synonyme:
- D12S1644;IL-4 Stat;IL-4-STAT;signal transducer and activator of transcription 6;signal transducer and activator of transcription 6, interleukin-4 induced;STAT, interleukin4-induced;STAT6B;STAT6C;transcription factor IL-4 STAT
- Weitere Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Versandbedingungen:
- Blue Ice