MVP/LRP antibody [1032]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX22376
Zusätzliche Namen:: major vault protein , LRP , VAULT1
Anwendung:: IHC, WB, IHC-P, IP
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Rat
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.
Klon:: 1032
Uniprot:: Q14764
Synonyme:: LRP;lung resistance-related protein;major vault protein;testicular secretory protein Li 30;VAULT1
Weitere Details:: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]