GTX22094
Cyclin E antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX22094
- Zusätzliche Namen:
- cyclin E1 , CCNE , pCCNE1
- Anwendung:
- ELISA, WB, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Unpurified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Filtered-steriled serum, 0.01% Sodium azide.
- Immunogen:
- A KLH conjugated peptide corresponding to a region near the carboxy terminus of human Cyclin E.
- Uniprot:
- P24864
- Synonyme:
- CCNE;G1/S-specific cyclin-E1;pCCNE1
- Weitere Details:
- Cyclin E is a regulatory subunit of cdk 2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
- Versandbedingungen:
- Blue Ice