GTX22043
MADD antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX22043
- Zusätzliche Namen:
- DENN , IG20 , MADD , MAP kinase activating death domain , RAB3GEP
- Anwendung:
- ELISA, WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Peptide corresponding to aa 1570-1588 of human MADD. This peptide sequence is identical to that of DENN and differs by one amino acid with rat GDP/GTP exchange protein RAB3-GEP.
- Uniprot:
- Q8WXG6
- Synonyme:
- DEEAH;DENN;differentially expressed in normal and neoplastic cells;IG20;insulinoma glucagonoma clone 20;MAP kinase-activating death domain protein;NEDDISH;Rab3 GDP/GTP exchange factor;rab3 GDP/GTP exchange protein;RAB3GEP;RabGEF
- Weitere Details:
- Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice