TIMP2 antibody [3A4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX21828
Zusätzliche Namen:: TIMP metallopeptidase inhibitor 2 , CSC-21K , DDC8
Anwendung:: WB, IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Purified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.09% Sodium azide.
Immunogen:: BALB/C mice were injected with a synthetic peptide from the N-terminal region of human TIMP-2.
Klon:: 3A4
Uniprot:: P16035
Synonyme:: CSC-21K;DDC8;metalloproteinase inhibitor 2;testicular secretory protein Li 57;tissue inhibitor of metalloproteinases 2
Weitere Details:: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]