GTX21667
CCR3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX21667
- Zusätzliche Namen:
- CC motif chemokine receptor 3,CCCKR3,CCR3,CD193,CKR3,CMKBR3,C-C motif chemokine receptor 3
- Anwendung:
- ELISA, IHC, WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- 10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
- Immunogen:
- C-VETFGTTSYYDDVGLLCEKADTRALMA 28 amino acid synthetized corresponding to aa 8-34 (cysteine added for coupling) of the N-terminal domain of human CCR3
- Uniprot:
- P51677
- Synonyme:
- b-chemokine receptor;C C CKR3;C-C chemokine receptor type 3;C-C CKR-3;CC chemokine receptor 3;CC-CKR-3;CCR-3;CD193;chemokine (C-C motif) receptor 3;CKR 3;CKR3;CMKBR3;eosinophil CC chemokine receptor 3;eosinophil eotaxin receptor
- Weitere Details:
- The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
- Versandbedingungen:
- Blue Ice