GTX20204
Ogg1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX20204
- Zusätzliche Namen:
- 8-oxoguanine DNA glycosylase , HMMH , HOGG1 , MUTM , OGH1
- Anwendung:
- ELISA, Flow Cytometry, WB, IHC-P, IHC-Fr, IF, ICC, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.05% Sodium azide.
- Immunogen:
- A peptide derived from human Ogg1 (within amino acids 1-100). [UniProt# O15527]
- Uniprot:
- O15527
- Synonyme:
- 8-hydroxyguanine DNA glycosylase;AP lyase;DNA-apurinic or apyrimidinic site lyase;HMMH;HOGG1;MUTM;N-glycosylase/DNA lyase;OGG1 type 1f;OGH1
- Weitere Details:
- This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice