GTX20058
APC antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX20058
- Zusätzliche Namen:
- APC regulator of WNT signaling pathway , BTPS2 , DP2 , DP2.5 , DP3 , GS , PPP1R46
- Anwendung:
- WB, IHC-Fr, IP
- Konzentration:
- 1.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Amino acids 1-433 N-terminal fragment of human APC (Adenomutons Polyposis Coli gene Chr 5q) fused to maltose binding protein.
- Uniprot:
- P25054
- Synonyme:
- adenomatosis polyposis coli tumor suppressor;adenomatous polyposis coli (APC);adenomatous polyposis coli protein;APC, WNT signaling pathway regulator;BTPS2;deleted in polyposis 2.5;DESMD;DP2;DP2.5;DP3;epididymis secretory sperm binding protein;GS;PPP1R46;protein phosphatase 1, regulatory subunit 46;truncated adenomatosis polyposis coli;WNT signaling pathway regulator
- Weitere Details:
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice