c-Myc antibody [9E10]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX20032
Zusätzliche Namen:: MRTL,MYC,MYCC,bHLHe39,cMyc,vmyc avian myelocytomatosis viral oncogene homolog,cmyc,MYC proto-oncogene, bHLH transcription factor
Anwendung:: ELISA, Flow Cytometry, WB, IF, ICC, IP
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: 2-8[o]C Do not freeze.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Filter-sterilized PBS, no preservatives.
Immunogen:: Synthetic peptide sequence corresponding to the C-terminal region (residues 408-439) of human c-myc conjugated to keyhole limpet hemocyanin.
Klon:: 9E10
Uniprot:: P01106
Synonyme:: avian myelocytomatosis viral oncogene homolog;bHLHe39;c-Myc;class E basic helix-loop-helix protein 39;MRTL;myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYCC;proto-oncogene c-Myc;transcription factor p64;v-myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog
Weitere Details:: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Versandbedingungen:: Blue Ice