Desmoglein 3 antibody [5H10]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX17502
Zusätzliche Namen:: desmoglein 3 , CDHF6 , PVA
Anwendung:: WB, IHC-P, IF, ICC, IP
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Tris-Glycine, 150mM NaCl, 0.05% Sodium azide.
Immunogen:: The extracellular domain of human Desmoglein 3 [Swiss-Prot# P32926]
Klon:: 5h10
Uniprot:: P32926
Synonyme:: 130 kDa pemphigus vulgaris antigen;ABOLM;cadherin family member 6;CDHF6;desmoglein-3;PVA
Weitere Details:: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq]