GTX17170
PHOX2A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX17170
- Zusätzliche Namen:
- paired like homeobox 2A , ARIX , CFEOM2 , FEOM2 , NCAM2 , PMX2A
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A.The immunogen is located within the last 50 amino acids of PHOX2A.
- Uniprot:
- O14813
- Synonyme:
- aristaless homeobox homolog;aristaless homeobox protein homolog;ARIX;arix homeodomain protein;ARIX1 homeodomain protein;CFEOM2;FEOM2;NCAM2;paired mesoderm homeobox protein 2A;Paired-like homeobox 2A;PMX2A
- Weitere Details:
- The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice