GTX17067
Apc10 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX17067
- Zusätzliche Namen:
- anaphase promoting complex subunit 10 , APC10 , DOC1
- Anwendung:
- ELISA, WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- APC10 antibody was raised against a 16 amino acid synthetic peptide near the center of human APC10.The immunogen is located within amino acids 60 - 110 of APC10.
- Uniprot:
- Q9UM13
- Synonyme:
- anaphase-promoting complex subunit 10;APC10;cyclosome subunit 10;DOC1
- Weitere Details:
- Apc10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]
- Versandbedingungen:
- Blue Ice