GTX17060-PEP
APC5 blocking peptide
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX17060-PEP
- Zusätzliche Namen:
- Anaphase Promoting Complex Subunit 5 , Apc5 , Anapc5
- Anwendung:
- Neutralisation
- Konzentration:
- 200 ug/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Hersteller:
- Genetex
- Buffer:
- PBS, 0.1% BSA, 0.02% Sodium azide.
- Immunogen:
- anaphase promoting complex subunit 5
- Spezies:
- Human
- Synonyme:
- anaphase-promoting complex subunit 5;APC5;cyclosome subunit 5
- Weitere Details:
- This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
- Versandbedingungen:
- Dry Ice