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  2. Polyclonal

GTX17012

ERp57 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX17012
Zusätzliche Namen:
protein disulfide isomerase family A member 3 , ER60 , ERp57 , ERp60 , ERp61 , GRP57 , GRP58 , HEL-S-269 , HEL-S-93n , HsT17083 , P58 , PI-PLC
Anwendung:
WB
Konzentration:
0.50 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Ammonium Sulfate Precipitated; Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Goat
Reaktivitäten:
Human, Mouse
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:
Peptide with sequence C-EEKPKKKKKAQEDL, from the C Terminus of the protein sequence according to NP_005304.3.
Uniprot:
P30101
Synonyme:
58 kDa glucose-regulated protein;58 kDa microsomal protein;disulfide isomerase ER-60;endoplasmic reticulum P58;endoplasmic reticulum resident protein 57;endoplasmic reticulum resident protein 60;epididymis secretory protein Li 269;epididymis secretory sperm binding protein Li 93n;ER protein 57;ER protein 60;ER60;ERp57;ERp60;ERp61;glucose regulated protein, 58kDa;GRP57;GRP58;HEL-S-269;HEL-S-93n;HsT17083;P58;phospholipase C-alpha;PI-PLC;protein disulfide isomerase-associated 3;protein disulfide-isomerase A3
Weitere Details:
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016]
Versandbedingungen:
Blue Ice