GTX16993
LIS1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX16993
- Zusätzliche Namen:
- platelet activating factor acetylhydrolase 1b regulatory subunit 1 , LIS1 , LIS2 , MDCR , MDS , NudF , PAFAH
- Anwendung:
- ELISA, WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- LIS1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human LIS1.The immunogen is located within amino acids 340 - 390 of LIS1.
- Uniprot:
- P43034
- Synonyme:
- LIS1;LIS2;lissencephaly 1 protein;Lissencephaly-1 protein;MDCR;MDS;NudF;PAF acetylhydrolase 45 kDa subunit;PAF-AH alpha;PAFAH;platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa);platelet-activating factor acetylhydrolase IB subunit beta
- Weitere Details:
- This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]
- Versandbedingungen:
- Blue Ice