GTX16977
SnoN antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX16977
- Zusätzliche Namen:
- SKI like proto-oncogene , SNO , SnoA , SnoI , SnoN
- Anwendung:
- ELISA, WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SnoN antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SnoN.The immunogen is located within the first 50 amino acids of SnoN.
- Uniprot:
- P12757
- Synonyme:
- SKI-like oncogene;ski-like protein;Ski-related oncogene;ski-related oncogene snoN;Ski-related protein;SNO;SnoA;SnoI;SnoN
- Weitere Details:
- The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Versandbedingungen:
- Blue Ice