GTX16976
MASP2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX16976
- Zusätzliche Namen:
- mannan binding lectin serine peptidase 2 , MAP19 , MASP-2 , MASP1P1 , sMAP
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of MASP2. The exact sequence is proprietary.
- Uniprot:
- O00187
- Synonyme:
- mannan binding lectin serine peptidase 2;mannan-binding lectin serine peptidase 1 pseudogene 1;mannan-binding lectin serine protease 1 pseudogene 1;mannan-binding lectin serine protease 2;mannose-binding lectin associated protein 19;mannose-binding lectin-associated serine protease 2;mannose-binding protein-associated serine protease 2;MAP-2;MAP19;MASP-2;MASP1P1;MBL-associated plasma protein of 19 kD;MBL-associated serine protease 2;small MBL-associated protein;sMAP
- Weitere Details:
- This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
- Versandbedingungen:
- Blue Ice