Thyroglobulin antibody [1D4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX16853
Zusätzliche Namen:: thyroglobulin , AITD3 , TGN
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: BALB/C mice were immunized with purified human thyroglobulin.
Klon:: 1D4
Uniprot:: P01266
Synonyme:: AITD3;TGN;thyroglobulin
Weitere Details:: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]