GTX16407
TTK antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX16407
- Zusätzliche Namen:
- TTK protein kinase , CT96 , ESK , MPH1 , MPS1 , MPS1L1 , PYT
- Anwendung:
- IHC, WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 517-856 of human TTK (NP_001160163.1).
- Uniprot:
- P33981
- Synonyme:
- cancer/testis antigen 96;CT96;dual specificity protein kinase TTK;ESK;monopolar spindle 1 kinase;monopolar spindle 1-like 1;MPH1;MPS1;MPS1L1;phosphotyrosine picked threonine kinase;phosphotyrosine picked threonine-protein kinase;PYT
- Weitere Details:
- This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- Versandbedingungen:
- Blue Ice