GTX16242
ARHGEF11 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX16242
- Zusätzliche Namen:
- Rho guanine nucleotide exchange factor 11 , GTRAP48 , PDZ-RHOGEF
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Bovine, Canine, Human, Mouse, Rat, Equine
- Buffer:
- PBS, 0.2% Gelatin, 0.05% Sodium azide.
- Immunogen:
- A portion of amino acids 1-50 of human ARHGEF11.
- Uniprot:
- O15085
- Synonyme:
- glutamate transporter EAAT4-associated protein 48;GTRAP48;PDZ-RHOGEF;Rho guanine exchange factor (GEF) 11;Rho guanine nucleotide exchange factor (GEF) 11;rho guanine nucleotide exchange factor 11;RhoA-specific guanine nucleotide exchange factor;RhoGEF glutamate transport modulator
- Weitere Details:
- Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice