GTX15916
GRAF antibody, C-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX15916
- Zusätzliche Namen:
- Rho GTPase activating protein 26 , GRAF , GRAF1 , OPHN1L , OPHN1L1
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.50 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Ammonium Sulfate Precipitated; Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-KTGLIPENYVEFL, from the C Terminus of the protein sequence according to NP_055886.1; NP_001129080.1.
- Uniprot:
- Q9UNA1
- Synonyme:
- GRAF;GRAF1;GTPase regulator associated with focal adhesion kinase;GTPase regulator associated with focal adhesion kinase pp125(FAK);oligophrenin-1-like protein;OPHN1L;OPHN1L1;rho GTPase-activating protein 26;Rho-type GTPase-activating protein 26
- Weitere Details:
- Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
- Versandbedingungen:
- Blue Ice