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GTX15537
TGF beta 3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX15537
- Zusätzliche Namen:
- transforming growth factor beta 3 , ARVD , ARVD1 , LDS5 , RNHF , TGF-beta3
- Anwendung:
- WB, IHC-P, IP
- Konzentration:
- 0.2 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 0.09% Sodium azide.
- Immunogen:
- A synthetic peptide derived from the C-terminus of the precursor form of human TGF beta 3.
- Uniprot:
- P10600
- Synonyme:
- ARVD;ARVD1;LDS5;prepro-transforming growth factor beta-3;RNHF;TGF-beta3;transforming growth factor beta-3 proprotein
- Weitere Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]
- Versandbedingungen:
- Blue Ice