GTX15086
Carbonic Anhydrase IX antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX15086
- Zusätzliche Namen:
- carbonic anhydrase 9 , CAIX , MN
- Anwendung:
- ChIP, ELISA, Flow Cytometry, WB, IHC-P, IHC-Fr, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Canine, Human, Mouse, Rat
- Buffer:
- PBS, 0.025% Sodium azide.
- Immunogen:
- A synthetic peptide made to a C-terminal sequence of human Carbonic Anhydrase IX (within residues 400-459) [UniProt Q16790]
- Uniprot:
- Q16790
- Synonyme:
- CA-IX;CAIX;carbonate dehydratase IX;carbonic anhydrase 9;carbonic anhydrase IX;carbonic dehydratase;membrane antigen MN;MN;P54/58N;pMW1;RCC-associated antigen G250;RCC-associated protein G250;renal cell carcinoma-associated antigen G250
- Weitere Details:
- Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice