GTX14918
NPR-A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX14918
- Zusätzliche Namen:
- natriuretic peptide receptor 1 , ANPRA , ANPa , GUC2A , GUCY2A , NPRA
- Anwendung:
- ELISA, IHC, WB, IF, ICC, IP
- Konzentration:
- 0.85 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Tris/Glycine, 0.5% BSA, 30% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to C terminal amino acids 1042-1057 of Human NPR-A protein. Seqence: VRTYWLLGERGCSTRG
- Uniprot:
- P16066
- Synonyme:
- ANP-A;ANPa;ANPR-A;ANPRA;atrial natriuretic peptide receptor 1;atrial natriuretic peptide receptor type A;atrionatriuretic peptide receptor A;GC-A;guanylate cyclase A;GUC2A;GUCY2A;natriuretic peptide A type receptor;natriuretic peptide receptor A;natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A);NPR-A;NPRA;testicular tissue protein Li 20
- Weitere Details:
- Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009]
- Versandbedingungen:
- Blue Ice