GTX14776
ACK1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX14776
- Zusätzliche Namen:
- tyrosine kinase non receptor 2 , ACK , ACK-1 , ACK1 , p21cdc42Hs
- Anwendung:
- ELISA, WB, IP
- Konzentration:
- 0.59-0.68 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Tris/Glycine, 0.5% BSA, 30% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Synthetic peptide taken within amino acid region 300-400 on ACK1 protein.
- Uniprot:
- Q07912
- Synonyme:
- ACK;ACK-1;ACK1;activated CDC42 kinase 1;activated Cdc42-associated kinase 1;activated p21cdc42Hs kinase;p21cdc42Hs;tyrosine kinase non-receptor protein 2
- Weitere Details:
- This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice