GTX14624
PDE11A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX14624
- Zusätzliche Namen:
- phosphodiesterase 11A , PPNAD2
- Anwendung:
- ELISA, IHC, WB, IF, ICC, IP
- Konzentration:
- 0.68 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Tris/Glycine, 0.5% BSA, 30% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Synthetic peptide conjugated to KLH, corresponding to C terminal amino acids 454-468 of human PDE11A.
- Uniprot:
- Q9HCR9
- Synonyme:
- cAMP and cGMP cyclic nucleotide phosphodiesterase 11A;cAMP and cGMP phosphodiesterase 11A;dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A;PPNAD2
- Weitere Details:
- The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice