GTX14282
WHSC2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX14282
- Zusätzliche Namen:
- negative elongation factor complex member A , NELF-A , P/OKcl.15 , WHSC2
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Chicken/Avian
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Immunogen Sequence: GI # 5032227, sequence 104-291 Recombinant WHSC2 protein
- Uniprot:
- Q9H3P2
- Synonyme:
- negative elongation factor A;NELF-A;P/OKcl.15;WHSC2;wolf-Hirschhorn syndrome candidate 2 protein
- Weitere Details:
- WHSC2 is expressed ubiquitously with higher levels in fetal than in adult tissues. Wolf Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt Rogers Danks syndrome. The encoded protein is found to be capable of reacting with HLA A2 restricted and tumor specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
- Versandbedingungen:
- Blue Ice