GTX14146
PD1 antibody [J116]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX14146
- Zusätzliche Namen:
- CD279,PD1,PDCD1,SLEB2,hPD1,hPDl,hSLE1,programmed cell death 1,PD-1
- Anwendung:
- Neutralisation
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Filter-sterilized PBS, no preservatives.
- Immunogen:
- programmed cell death 1
- Klon:
- J116
- Uniprot:
- Q15116, Q8IX89
- Synonyme:
- CD279;hPD-1;hPD-l;hSLE1;PD-1;PD1;programmed cell death 1 protein;programmed cell death protein 1;protein PD-1;SLEB2;systemic lupus erythematosus susceptibility 2
- Weitere Details:
- This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice