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GTX13900

PMS2 antibody [163C1251]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX13900
Zusätzliche Namen:
PMS1 homolog 2, mismatch repair system component , HNPCC4 , MLH4 , PMS2CL , PMSL2
Anwendung:
Flow Cytometry, WB, IHC-P
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein G Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human, Mouse
Buffer:
PBS, 0.05% Sodium azide.
Immunogen:
This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2; GenBank No. NP_000526.1.
Klon:
163C1251
Uniprot:
P54278
Synonyme:
DNA mismatch repair protein PMS2;HNPCC4;mismatch repair endonuclease PMS2;MLH4;MMRCS4;PMS1 homolog 2, mismatch repair protein;PMS1 protein homolog 2;PMS2 postmeiotic segregation increased 2;PMS2CL;PMSL2;postmeiotic segregation increased 2 nirs variant 6
Weitere Details:
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]
Versandbedingungen:
Blue Ice