DcR1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX13863
Zusätzliche Namen:: TNF receptor superfamily member 10c , CD263 , DCR1 , DCR1-TNFR , LIT , TRAIL-R3 , TRAILR3 , TRID
Anwendung:: WB
Konzentration:: 0.5 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Mouse
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Mouse
Buffer:: PBS, 0.2% Gelatin, 0.05% Sodium azide.
Immunogen:: This antibody was developed against a synthetic peptide corresponding to amino acids 155-168 ([BLAST]CSSSVSNPRNWLFL[/BLAST]) of mouse DcTrailR1; GenBank no: NP_077252.2.
Uniprot:: O14798
Synonyme:: antagonist decoy receptor for TRAIL/Apo-2L;CD263;cytotoxic TRAIL receptor-3;DCR1;DCR1-TNFR;decoy receptor 1;decoy TRAIL receptor without death domain;LIT;lymphocyte inhibitor of TRAIL;TNF-related apoptosis-inducing ligand receptor 3;TRAIL receptor without an intracellular domain;TRAIL-R3;TRAILR3;TRID;tumor necrosis factor receptor superfamily member 10C;tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Weitere Details:: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq]

Versandbedingungen:: Blue Ice