GTX13691
APEX2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX13691
- Zusätzliche Namen:
- apurinic/apyrimidinic endodeoxyribonuclease 2 , APE2 , APEXL2 , XTH2 , ZGRF2
- Anwendung:
- WB
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.05% BSA, 0.02% Sodium azide.
- Immunogen:
- This antibody was generated by immunizing rabbits with EELRALDSEGRALLTQHKI (aa122-140) and GQAKTSEAKDEKELRTSF (aa438-455) peptides of human APEX2.
- Uniprot:
- Q9UBZ4
- Synonyme:
- AP endonuclease 2;AP endonuclease XTH2;APE2;APEX nuclease (apurinic/apyrimidinic endonuclease) 2;APEX nuclease 2;APEX nuclease-like 2;APEXL2;Apurinic-apyrimidinic endonuclease 2;apurinic/apyrimidinic endonuclease-like 2;DNA-(apurinic or apyrimidinic site) endonuclease 2;DNA-(apurinic or apyrimidinic site) lyase 2;XTH2;ZGRF2;zinc finger, GRF-type containing 2
- Weitere Details:
- Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq]
- Versandbedingungen:
- Blue Ice