GNAS (R201H Mutant) antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX135413
Zusätzliche Namen:: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus , 5530400H20Rik , A930027G11Rik , C130027O20Rik , GPSA , GSP , Galphas , Gnas1 , Gnasxl , Gs-alpha , Gsa , Nesp , Nesp55 , Nespl , Oed-Sml , Oedsml , P1 , P2 , P3 , PHP1A , PHP1B , POH , SCG6
Anwendung:: WB, IF, ICC
Konzentration:: 0.4 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human, Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Carrier-protein conjugated synthetic peptide surrounding mutant R201H of mouse GNAS. The exact sequence is proprietary.
Uniprot:: P63094, Q6R0H6, Q6R0H7, Q9Z0F1
Synonyme:: 5530400H20Rik;A930027G11Rik;adenylate cyclase-stimulating G alpha protein;alternative gene product encoded by XL-exon;C130027O20Rik;extra large alphas protein;G;Ga;Galphas;Gn;Gnas1;Gnasxl;GPSA;Gs alpha subunit;Gs-;Gs-alpha;Gsa;GSP;N;Nes;Nesp;Nesp55;Nespl;neuroendocrine secretory protein 55;Oed;Oed-Sml;Oedsml;P;P1;P2;P3;PHP1A;PHP1B;POH;protein ALEX;protein GNAS;protein SCG6 (secretogranin VI);SCG;SCG6;secretogranin VI;stimulatory G-protein alpha subunit;XL
Weitere Details:: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, which is commonly found in imprinted genes and correlates with transcript expression. This gene has an antisense transcript. One of the transcripts produced from this locus, and the antisense transcript, are both paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Additional transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2015]

Versandbedingungen:: Blue Ice