GTX134734
FMRP antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX134734
- Zusätzliche Namen:
- fragile X mental retardation 1 , FMRP , FRAXA , POF , POF1
- Anwendung:
- WB
- Konzentration:
- 1.92 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human FMRP. The exact sequence is proprietary.
- Uniprot:
- Q06787
- Synonyme:
- FMRP;fragile X mental retardation 1;fragile X mental retardation protein 1;FRAXA;POF;POF1;synaptic functional regulator FMR1;truncated FMRP
- Weitere Details:
- The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
- Versandbedingungen:
- Blue Ice