GTX134466
LIFR antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX134466
- Zusätzliche Namen:
- LIF receptor alpha , CD118 , LIF-R , SJS2 , STWS , SWS
- Anwendung:
- WB
- Konzentration:
- 0.71 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the Intracellular domain of human LIFR. The exact sequence is proprietary.
- Uniprot:
- P42702
- Synonyme:
- CD118;CD118 antigen;leukemia inhibitory factor receptor;leukemia inhibitory factor receptor alpha;LIF receptor alpha;LIF-R;SJS2;STWS;SWS
- Weitere Details:
- This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
- Versandbedingungen:
- Blue Ice