GTX133980
c-Abl (phospho Tyr245) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX133980
- Zusätzliche Namen:
- c-abl oncogene 1, non-receptor tyrosine kinase , AI325092 , Abl , E430008G22Rik , c-Abl
- Anwendung:
- WB
- Konzentration:
- 1.08 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Carrier-protein conjugated synthetic peptide surrounding phospho Tyr245 of mouse c-Abl. The exact sequence is proprietary.
- Uniprot:
- P00520
- Synonyme:
- Abelson murine leukemia oncogene;abelson murine leukemia viral oncogene homolog 1;Abelson tyrosine-protein kinase 1;Abl;AI325092;c-A;c-Abl;c-abl oncogene 1, receptor tyrosine kinase;c-abl protein, type I;c-abl protein, type II;c-abl protein, type III;E430008G22Rik;p150;proto-oncogene c-Abl;proto-oncogene tyrosine-protein kinase ABL1;tyrosine-protein kinase ABL1;v-abl Abelson murine leukemia oncogene 1
- Weitere Details:
- Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
- Versandbedingungen:
- Blue Ice