GTX133798
GFI1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX133798
- Zusätzliche Namen:
- growth factor independent 1 transcriptional repressor , GFI-1 , GFI1A , SCN2 , ZNF163
- Anwendung:
- WB
- Konzentration:
- 1.27 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human GFI1. The exact sequence is proprietary.
- Uniprot:
- Q99684
- Synonyme:
- GFI-1;GFI1A;growth factor independence-1;growth factor independent 1 transcription repressor;growth factor independent protein 1;SCN2;zinc finger protein 163;zinc finger protein Gfi-1;ZNF163
- Weitere Details:
- This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice