GTX13339
GRPR antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX13339
- Zusätzliche Namen:
- gastrin releasing peptide receptor , BB2 , BB2R , GRPR
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Canine, Human, Porcine, Rabbit, Equine
- Buffer:
- PBS, 0.1% Sodium azide.
- Immunogen:
- Synthetic 18 amino acid peptide from 2nd extracellular domain of human GRPR.
- Uniprot:
- P30550
- Synonyme:
- BB2;BB2R;bombesin receptor 2;BRS2;gastrin-releasing peptide receptor;GRP-preferring bombesin receptor;GRP-R
- Weitere Details:
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice