GTX133272
CASPR antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX133272
- Zusätzliche Namen:
- contactin associated protein-like 1 , AI841080 , Caspr , NCP1 , Nrxn4 , p190 , shm
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.53 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the Intracellular domain of mouse CASPR. The exact sequence is proprietary.
- Uniprot:
- O54991
- Synonyme:
- AI841080;C;Caspr;caspr1;contactin-associated protein 1;MHDNIV;NC;NCP1;neurexin 4 (contactin associated protein);neurexin IV;neurexin-4;Nr;Nrxn4;p;p19;p190;paranodin;sh;shm
- Weitere Details:
- Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells. Mice that lack CNTAP1 exhibit tremor, ataxia, and significant motor paresis. Normal paranodal junctions fail to form, and the organization of the paranodal loops is disrupted. Contactin is undetectable in the paranodes, and potassium channels are displaced from the juxtaparanodal into the paranodal domains. Also results in a severe decrease in peripheral nerve conduction velocity.
- Versandbedingungen:
- Blue Ice