GTX133206
Contactin 1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX133206
- Zusätzliche Namen:
- contactin 1 , AW495098 , CNTN , F3cam , usl
- Anwendung:
- WB, IHC-Fr
- Konzentration:
- 2.25 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse Contactin 1. The exact sequence is proprietary.
- Uniprot:
- P12960
- Synonyme:
- AW495098;CN;CNTN;contactin-1;F3ca;F3cam;neural cell surface protein F3;u;usl
- Weitere Details:
- Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.
- Versandbedingungen:
- Blue Ice