CCR1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX13240
Zusätzliche Namen:: CC motif chemokine receptor 1,CCR1,CD191,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1,C-C motif chemokine receptor 1
Anwendung:: ELISA, Flow Cytometry, IHC, WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Goat
Reaktivitäten:: Human
Buffer:: 10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.
Immunogen:: Synthetic peptide TEDYDTTTEFDYGDATPC corresponding to amino acids 7-24 of the N-terminal extracellular domain of human CCR1
Uniprot:: P32246
Synonyme:: C-C chemokine receptor type 1;C-C CKR-1;CC-CKR-1;CCR-1;CD191;chemokine (C-C motif) receptor 1;CKR-1;CKR1;CMKBR1;HM145;LD78 receptor;macrophage inflammatory protein 1-alpha receptor;MIP-1alpha-R;MIP1aR;RANTES receptor;RANTES-R;SCYAR1
Weitere Details:: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice