GTX132293
PHD2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX132293
- Zusätzliche Namen:
- egl-9 family hypoxia inducible factor 1 , C1orf12 , ECYT3 , HALAH , HIF-PH2 , HIFPH2 , HPH-2 , HPH2 , PHD2 , SM20 , ZMYND6
- Anwendung:
- WB, IHC-Fr, IF, ICC
- Konzentration:
- 0.99 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PHD2. The exact sequence is proprietary.
- Uniprot:
- Q9GZT9
- Synonyme:
- C1orf12;ECYT3;egl nine homolog 1;egl nine-like protein 1;HALAH;HIF-PH2;HIF-prolyl hydroxylase 2;HIFPH2;HPH-2;HPH2;hypoxia-inducible factor prolyl hydroxylase 2;PHD2;prolyl hydroxylase domain-containing protein 2;SM-20;SM20;zinc finger MYND domain-containing protein 6;ZMYND6
- Weitere Details:
- The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq]
- Versandbedingungen:
- Blue Ice