GTX131449
HIP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX131449
- Zusätzliche Namen:
- huntingtin interacting protein 1 , HIP-I , ILWEQ , SHON , SHONbeta , SHONgamma
- Anwendung:
- WB
- Konzentration:
- 0.56 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human HIP1. The exact sequence is proprietary.
- Uniprot:
- O00291
- Synonyme:
- HIP-I;huntingtin-interacting protein 1;huntingtin-interacting protein I;ILWEQ;SHON;SHONbeta;SHONgamma
- Weitere Details:
- The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice